Sarmento studied painting and architecture at the Lisbon School of Fine Arts. He began exhibiting film, video, sound, painting, sculpture, installation and multimedia in the early seventies, but also developed several site-specific projects. He has exhibited his work extensively around the world in solo and group shows. Sarmento represented Portugal at the Venice Biennial in 1997. His work is represented in several museums and private collections, including an artist room showing at London's Tate Modern in 2010.